Allogeneic Stem Cell Transplantation in Children with Acquired Aplastic Anemia

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Allogeneic hematopoietic stem cell transplantation in children with aplastic anemia.

The aim of this study was to prospectively investigate the efficacy and safety of fully matched allogeneic hematopoietic stem cell transplants in children with severe aplastic anemia in China. A total of twenty patients with severe aplastic anemia were enrolled in our study. Thirteen cases underwent transplantation with fully human leukocyte antigen (HLA)-matched, granulocyte-colony stimulating...

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Allogeneic peripheral blood stem cell transplantation in aplastic anemia.

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hematopoietic stem cell transplantation in patients with severe acquired aplastic anemia: iranian experience

introduction: severe acquired aplastic anemia (saa) is a rare disease and matched related hematopoietic stem cell transplantation (hsct) is the treatment of choice especially in pediatric patients. immunosuppressive therapy is the alternative treatment in patients who do not have a donor. we retrospectively analyzed patients who received allogeneic hsct at our institution. methods: between 1991...

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Haploidentical hematopoietic stem cell transplantation in children and adolescents with acquired severe aplastic anemia

Severe aplastic anemia (SAA) is a life-threatening disorder for which allogeneic hematopoietic stem cell transplantation (HSCT) is the current available curative treatment. HSCT from matched sibling donors (MSDs) is the preferred therapy for children with acquired SAA. For patients who lack MSDs, immunosuppressive therapy (IST) is widely accepted as a first-line treatment before considering HCT...

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Allogeneic transplantation for aplastic anemia.

OBJECTIVE To discuss the role of allogeneic transplantation for the treatment of severe aplastic anemia. METHODS Published reports for treatment of severe aplastic anemia were searched with Medline. Search terms included severe aplastic anemia, HLA-matched sibling, unrelated donor, hematopoietic stem cell transplantation. RESULTS Survival after HLA-matched sibling donor transplantation is a...

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ژورنال

عنوان ژورنال: Turkish Journal of Pediatric Disease

سال: 2017

ISSN: 1307-4490,2148-3566

DOI: 10.12956/tjpd.2017.328